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A gene involved in the brain’s overnight cleaning system may change how strongly poor sleep affects Alzheimer’s-related brain changes. The findings point toward more personalized prevention strategies based on both genetics and sleep habits.
Regular exercise may help the brain clear away harmful waste that can build up with age. Researchers found that physical activity supports several processes linked to the brain’s glymphatic cleanup system, including better sleep, lower inflammation, and healthier blood vessels. Because this waste-removal system becomes increasingly important as we get older, exercise could play a meaningful role in protecting against cognitive decline.